Dec 2025
Abdel’s work titled “Resource Competition and Growth Dilution Modulate Synthetic Gene Cascade Dynamics” has been accepted by ACS Synthetic Biology.
Nov 2025

Rong’s paper is online at Cell.
ASU news: Using nature’s playbook to keep engineered cells on script
Genetic Engineering & Biotechnology News: Stabilizing Synthetic Gene Circuits Using Transcriptional Condensates
Oct 2025
Xiaojun gives an invited talk at the Department of Molecular & Cellular Biology at the University of Arizona.
Sept 2025

Sadikshya’s work is online at ACS Synthetic Biology.

Rixin’s paper is online at Nucleic Acids Research.
Rixin’s plasmids are now can be found in Addgene.
June 2025
Xiaojun gives a talk at the 2025 Synthetic Biology: Engineering, Evolution, & Design (SEED) conference.
Sadikshya gives a poster presentation at the 2025 Synthetic Biology: Engineering, Evolution, & Design (SEED) conference.
May 2025
Rixin’s manuscript titled “Integrating Recombinase-Based Feedback and Feedforward Control for Optimal Resource Decoupling” is shared on BioRxiv
Sadikshya’s manuscript titled “CRISPRi-Linked Multi-Module Negative Feedback Loops to Address Winner-Take-All Resource Competition” is shared on BioRxiv.
Prof. Alexander Darlington from the University of Warwick visits our lab and gives a seminar.
Abdelrahman and Sadikshya presented their research at the EBRC Annual Meeting in the beautiful city of Seattle.
April 2025
Hanah’s paper on Resource Competition-Driven Bistability and Stochastic Switching is online now.
April 2025
High school student Annie Chen has finished her internship in our lab and has recently been admitted to Rice University.
High school student Ceyda Oz has completed her SCENE project in our lab and won 2nd place in cellular and molecular biology at the Arizona Science & Engineering Fair.
March 2025
The lab went to Flagstaff for a ski trip.
Hanah’s paper on Resource Competition-Driven Bistability and Stochastic Switching is accepted by Plos Comp Biol.
Feb 2025
Suchana’s research, ‘Noise Reduction in Resource-Coupled Multi-Module Gene Circuits through Antithetic Feedback Control,’ is now online at the 2024 IEEE 63rd Conference on Decision and Control (CDC).
Jan 2025
Xiaojun gives an talk at the Stochastic Physics in Biology Gordon Research Conference in CA.
Dec 2024
Xiaojun gives an invited talk at the 2024 Conference on Decision and Control in Milan.
Xiaojun gives an invited talk at the Inaugural SynBYSS conference, University of Hawaii at Manoa, Honolulu, Hawaii
Suchana gives a Flash Talk and Poster Presentation at the 23rd International Conference on Systems Biology, Mumbai, India. She got the first place prize.
Nov 2024
Suchana’s research work is now online at ACS Synthetic Biology.
Rong’s research work titled ”Phase Separation to Resolve Growth-Related Circuit Failures’ is shared in BioRxiv.
Sept 2024
Xiaojun gives a presentation at the ASU Biological Physics & Structural Discovery Seminar.
July 2024
Xiaojun gives a presentation at the annual meeting of the Korean Society for Mathematical Biology and the Society for Mathematical Biology in Seoul.
May 2024
Suchana’s research work titled ”Noise Reduction in Resource-Coupled Multi-Module Gene Circuits through Antithetic Feedback Control’ is shared in BioRxiv.
March 2024
Xiaojun gives a presentation at presentation at the University of Manitoba, Canada
Feb 2024
Xiaojun gives a presentation at the Gogec Conference.
Feb 2024

Austin’s review paper entitled ‘Context-Dependent Redesign of Robust Synthetic Gene Circuits’ is published in Trends in Biotechnology.
Dec 2023
Austin’s work on ‘Enhancing circuit stability under growth feedback with supplementary repressive regulation’ is published at Nucleic Acids Research.
Nov 2023
Dr. Tian attends the NSF Career Awardee Conference.
October 2023
Suchana joins the lab. Welcome, Suchana!
Aug 2023
Rixin joins the lab. Welcome, Rixin!
June 2023
Austin successfully defended his Ph.D. dissertation! Congratulations, Dr. Stone!
June 2023
Collaboration project on ‘Effects of growth feedback on gene circuits: A dynamical understanding’ led by Lingwei in Dr. Lai’s lab is shared on Biorxiv.
June 2023
Juan’s paper on ‘Growth feedback confers cooperativity in resource-competing synthetic gene circuits’ is published at Chaos, Solitons & Fractals. Congratulations, Juan!
May 2023
Xiaojun will be promoted to Associate Professor and granted Tenure effective in the Fall.
April 2023
Xiaojun receives SBHSE Outstanding Assistant Professor Award. Congratulations!
Feb 2023
Austin passed his prospectus exam. One more step to be a Ph.D. Keep it up!
Jan 2023
Juan starts his job as a postdoc in the lab!
Dec 2022
Austin passed his comprehensive exam. Good job, Austin.
Hanah’s collaboration project with Halden lab on Covid19 pandemic using the established wastewater monitoring network is officially published online in The Lancet Microbe.
Nov 2022
Xiaojun gives a talk at AIChE.
Austin’s paper is online now. Check it out ACS Synthetic Biology.
Oct 2022
Juan successfully defended his Ph.D. dissertation! Congratulations, Dr. Melendez-Alvarez!
Xiaojun gives a talk at CELLS 2022 (Computing among Cells Workshop) at DISC 2022.
Austin’s project on the NCR Feedforward Controller has been accepted by ACS Synthetic Biology.
Sept 2022
Juan’s paper is online now PLoS Computational Biology. Check it out.
Aug 2022
Sadikshya and Abdelrahaman join the lab! Welcome!
Juan’s paper is accepted by PLoS Computational Biology. Congratulations, Juan.
July 2022
The collaborative paper on the biological memory effect in microbial fuel cell biosensors with Jianwei is accepted by IEEE Sensors Journal.
June 2022
Juan, Austin, and Xiaojun share our research at the qBio conference.
May 2022
Juan passes his prospectus. Congratulations, Juan. One more step to be Dr. Melendez-Alvarez.
April 2022
Hanah successfully defended her dissertation. Congratulations, Dr. Goetz.
March 2022
Xiaojun gives an invited talk and poster at the APS March Meeting.
Feb 2022
Xiaojun is featured in ASU-FSE Full Circle story
https://fullcircle.asu.edu/faculty/how-to-entertain-a-gene-circuit-without-exhausting-its-host/
Feb 2022
Austin gives poster presentations at the 66th Biophysical Society Annual Meeting.
Feb 2022
Both Xiaojun and Rong give oral presentations at the Winter-Qbio conference.
Feb 2022
Our work on the Double‐Edged Role of Resource Competition in Gene Expression Noise and Control is online now. Check it out.
Jan 2022
Xiaojun receives an NSF Career award.
Jan 2022
Hanah and Austin’s work on the ‘Double-edged role of resource competition in gene expression noise and control’ is accepted by Advanced Genetics. Congratulations, everyone.
Nov 2021
Xiaojun gives a virtual seminar in the Department of Computational and Systems Biology at the Univerisity of Pittsburgh. So excited to be back to PITT.
Nov 2021
Diego and Juan’s paper is accepted by PLoS Computational Biology. Here is the Link. Congratulations, everyone.
Nov 2021
Xiaojun gives one presentation at NSF Workshop: Systems and Control Theory for Synthetic Biology.
Nov 2021
Hanah and Austin’s collaboration work is now shared in BioRxiv
Oct 2021
Xiaojun gives a talk at UCI CMCF 2021 Annual Symposium.
Oct 2021
Xiaojun gives a talk at #SynBYSS. Here is the record on Youtube.
Oct 2021
Hanah passed her Prospectus Exam! Congratulations, Hanah.
Sept 2021
Dr. Xiling Shen visits our lab and give us a wonderful talk for our BME seminar.
Sept 2021
The paper on fibrotic kidney local microenvironment, led by Dr. Zhou, is online. Great work, the Team!
Sept 2021
Juan passed his Qualifying Exam. Congratulations, Juan.
Aug 2021
Xiaojun was awarded a 5-yr R35 MIRA grant.
Aug 2021
Austin’s paper on controlling Winner-Take-All Resource Competition is online. Check it out here https://ieeexplore.ieee.org/abstract/document/9483381
July 2021
Xiaojun gives International Mammalian Synthetic Biology Workshop (mSBW).
June 2021
Excited to see the plasmids from our lab shared in Addgene finally.
https://www.addgene.org/Xiaojun_Tian/
May 2021
Xiaojun gives a talk about NCR controller for resource competition at 2021 American Control Conference (ACC).
May 2021
Congratulations to Juan and Austin on being awarded the Biological Design Excellence Award and SBHSE Graduate Excellence award respectively! Excellent Job, Juan and Austin! So proud of you!
April 2021
Hanah gives a wonderful invited talk at the Biological Modeling and Mining (BMM) one-day event organized by Dr. Minghan Chen and Dr. Natalia Khuri at Wake Forest University. Great Job, Hanah.
April 2021
Our paper titled ‘Emergent Damped Oscillation Induced by Nutrient-Modulating Growth Feedback’ is published at ACS Synthetic Biology. Congratulations to all the authors.
April 2021
Diego Barra Avila successfully defended his Master Thesis. Congratulations, Diego.
March 2021
Xiaojun gives a talk for MPET VFM Seminar at Mayo Clinic.
Feb 2021
Our new work on Emergent Oscillation Induced by Nutrient-Modulating Growth Feedback is shared online. Check it out here. https://www.biorxiv.org/content/10.1101/2021.02.09.430447v1
Feb 2021

Our paper on ‘WTA’ resource competition is online at Nature Communications.
‘Behind the paper’ at Nature Research Bioengineering Community: Unfair Yet Controllable Competition Between Synthetic Gene Circuits: Harnessing ‘Winner-Takes-All’ Resource Competition Through ‘Division of Labor’
Jan 2021
Our paper on NCR controller for resource competition is accepted by 2021 American Control Conference (ACC). Congratulations on your first publication, Austin. Good Job.
Jan 2021
Our paper on resource competition is accepted by Nature Communications. Excellent news for the great start of 2021. Thanks for all your contributions, everyone.
Dec 2020
Xiaojun, Austin, Juan’s talks at the 1st International BioDesign Research Conference are online. Please leave a comments if you have any questions or suggestions. Thanks.
Nov 2020
Hanah passed her comprehensive exam. Congratulations, Hanah.
Nov 2020
Xiaojun, Austin, Juan’s abstracts are accepted as Oral Presentation by the 1st International BioDesign Research Conference. Congratulations!
Nov 2020
Xiaojun gives a talk at the ASU Biological Design Seminar.
Nov 2020
Xiaojun gives a micro talk at the 3rd Annual Conference on Quantitative Approaches in Biology.
Oct 2020
Austin Stone did an excellent Oral Presentation at the 2nd International NanoBioEngineering Virtual Congress.
Oct 2020
Dr. Matthew Bennett visit us virtually and gives us a seminar ‘Engineering Multicellular Systems in Bacteria‘.
Oct 2020
Dr. Ido Golding visit us virtually and gives us a seminar ‘Illuminating Bacterial Individuality‘.
Sept 2020
Austin Stone, Hanah Goetz, and Juan Melendez-Alvarez’a abstracts have been selected for poster presentation by the Cell Bio Virtual 2020-An Online ASCB|EMBO Meeting. Congratulations
June 2020
Xiaojun Tian presents the work of resource competition at Evolutionary and ecological systems biology talks, a web-based seminar series organized by Dr Jeff Gore at MIT. https://sites.google.com/view/eesb-talks/home
May 2020
Our new work on resource competition is shared online. Take a look. https://www.biorxiv.org/content/10.1101/2020.05.23.103259v1
May 2020
Congratulations to Hanah on being awarded the Outstanding Graduate Student Award in the Biological Design Graduate Program in SEMTE! Excellent Job, Hanah! So proud of you!
April 2020
Our work is featured in ASU news:
https://fullcircle.engineering.asu.edu/research/fulton-researchers-reveal-new-understanding-of-synthetic-gene-circuits/
April 2020
Our first synthetic biology paper ‘Topology-dependent interference of synthetic gene circuit function by growth feedback‘ is online at Nature Chemical Biology. Congratulations, everyone!

March 2020
Our paper ‘A Plausible Accelerating Function of Partial EMT States in Cancer Metastasis‘ is online at PLOS Computational Biology. Congratulations, Hanah and Juan.

April 2020
Xiaojun’s paper ‘Sequential Wnt Agonist then Antagonist Treatment Accelerates Tissue Repair and Minimizes Fibrosis‘ is published at iScience. Congratulations, everyone!

March 2020
Dr. Huimin Zhao from the University of Illinois, Urbana-Champaign visits our lab.
Feb 2020
Rong and Xiaojun give two talks and two posters on our recent research circuit-host interactions at the Winter-Qbio conference.
Jan 2020
Hanah is attending ‘A Short Course in Systems Biology: A Foundation for Interdisciplinary Careers’ organized by UC IRVINE/CCBS.
Jan 2020
Two papers accepted on the first day of Chinese New Year! Exciting! Congratulations, everyone!
- Zhang, R., Li J., Melendez-Alvarez, J., Chen, X., Sochor, P., Zhang, Q., Goetz H, Ding, T., Wang, X., Tian, X.-J., Topology-Dependent Interference of Synthetic Gene Circuits by Growth Feedback. Nat.Chem.Biol. 2020. (Accepted)
- Goetz, H., Melendez-Alvarez, J., Chen, L, Tian, X.-J. A Plausible Accelerating Function of Partial EMT States in Cancer Metastasis. PLOS Computational Biology. 2020. (Accepted)
Nov 2019
Our recent work titled ‘A Plausible Accelerating Function of Intermediate States in Cancer Metastasis’ is shared on biorxiv. Check it here.
Oct 2019
Dr. Wenying Shou from Fred Hutchinson Cancer Research Center visits our lab.
Oct 2019
Xiaojun gives a talk and a poster at the 2nd Annual Symposium on Multiscale Cell Fate.
Oct 2019
Xiaojun gives a talk, Juan and Hanah give two posters at the ICMA VII. Hanah got the Best Poster Award! Congratulations!
Sep 2019
Andrea Borsenik, Austin Stone and Rishabh Guttal join the lab. Welcome!
Aug 2019
Our first experimental work is shared on biorxiv. Check it here.
Aug 2019
Xiaojun gives a poster at the qBio2019.
Xiaojun’s NSF proposal is awarded. Congratulations!
June 2019
Xiaojun gives a talk at the conference ‘Quantitative Biology 2019: Dynamic Signaling in Cells and Embryos’.
May 2019
Hanah, Juan, and Xiaojun give two posters in the ‘Statewide Symposium in Regenerative Medicine’.
May 2019
The work collaborated with Dr. Xiao Wang lab on ratio control is finally accepted by ACS Synthetic Biology! Congratulations!
May 2019
Vishvak Rangarajan joins the lab! Welcome!
May 2019
Renaad, Shaheeda, Jonathan successfully defended their applied projects. Congratulations!
April 2019
March 2019
Chase Frailey and Daniel Khan join the lab! Welcome!
January 2019
Wesley Groves and Diego Barra join the lab! Welcome!
January 2019
Xiaojun’s review ‘Investigating epithelial-to-mesenchymal transition with integrated computational and experimental approaches’ is published in Physical Biology! Congratulations!
January 2019
Manuela and Hanah’s review Modeling ncRNA-Mediated Circuits in Cell Fate Decision is published as a book chapter! Congratulations!
January 2019
Shaheeda and Jonathan join the lab! Welcome!
December 2018
September 2018
I am serving as a guest editor for a special issue on a special issue on “Mathematical Modeling of Cell Fate Decision-Making, Predicting and Controlling”, which will be published in the journal Mathematical Biosciences and Engineering. This special issue intends to focus on the mathematical model developments and theoretical analysis for biological systems with an emphasis on work related to cell fate decisions. The work should have a strong connection with biology. Experimental verification is appreciated but not required. More information can be found HERE.
September 2018
July 2018
April 2018
April 2018
Xiaojun’s collaborative work with Jingyu Zhang and Jianhua Xing is accepted by npj Systems Biology and Applications. Congratulations!!
April 2018
Rong Zhang joins our lab as a Lab Technician! Welcome, Dr. Zhang.
March 2018
Fei Ye joins our lab as a visiting scholar! Welcome, Prof. Fei Ye.
February 2018
Xiaojun gives a talk at Math Bio Seminar.
January 2018
Xiaojun gives proseminar for Biological Design doctoral students.
January 2018
Manuela Vanegas Ferro, Erin Sussex, and Anna Rothweil join our lab! Welcome, Manuela, Erin, and Anna.
December 2017
Xiaojun gives three posters at the 8th International Meeting on Epithelial-Mesenchymal Transition @ Houston, TX.
November 2017
Xiaojun gives a talk at the BME 591 Seminar.
October 2017
Xiaojun gives a poster presentation at the Mayo Clinic / ASU Symposium.
September 2017
Jason Zhang joins our lab! Welcome, Jason.
September 2017
Zhiwei Yang joins our lab! Welcome, Zhiwei.
September 2017
Xiaojun gives a talk at the joint group meeting with Prof. Junwen Wang’s lab.
August 2017
Xiaojun arrives at campus on August 13.
August 2017
Xiaojun gives a talk at the 2017 International Conference on Systems Biology in Blacksburg, Virginia on August 6-12.
August 2017
The Tian Laboratory at the Arizona State University is launched. We’re currently looking for motivated graduate students and postdocs. Join us!
April 2017
Xiaojun accepts a tenure-track Assistant Professor position at the Arizona State University.
